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Femoral and Tibial Bone Loss in Two-Stage Revision Total Knee Arthroplasty for Periprosthetic Joint Infection and Its Association with the Time to Reimplantation: A Single-Center, Retrospective Clinical Study

Femoral and Tibial Bone Loss in Two-Stage Revision Total Knee Arthroplasty for Periprosthetic Joint Infection and Its Association with the Time to Reimplantation: A Single-Center, Retrospective Clinical Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105561
Enrollment
Unknown
Registered
2025-07-07
Start date
2025-07-10
Completion date
Unknown
Last updated
2025-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Two-stage revision of the knee prosthesis

Interventions

Postoperative Revision Group:None

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Aged >=18 years, regardless of gender; (2) Diagnosed with periprosthetic joint infection (PJI) according to the 2018 International Consensus Meeting (ICM) criteria for musculoskeletal infection, following total knee arthroplasty; (3) Scheduled for two-stage revision of the knee prosthesis.

Exclusion criteria

Exclusion criteria: (1) Absence or compromised quality of radiographic documentation during any of the following phases: pre-explantation, interim period, or post-reimplantation; (2) Incomplete clinical records.

Design outcomes

Primary

MeasureTime frame
Bone defect score;Infection eradication rate;—

Secondary

MeasureTime frame
Incidence of spacer-related mechanical complications;Postoperative reoperation rate;—

Countries

China

Contacts

Public ContactZongke Zhou

Department of Orthopedics and Orthopedic Research Institute, West China Hospital, Sichuan University

zhouzongke@scu.edu.cn+86 189 8060 1028

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026