Acute altitude sickness
Conditions
Interventions
Non oxygen group:Non oxygen
Low flow oxygen inhalation group:2L/min flow rate oxygen inhalation, 4 hours/day, lasting for 1 week
High flow oxygen inhalation group:4L/min flow rate oxygen inhalation, 4 hours/day, lasting for 1 week
Ladder deoxygenation group:Oxygen inhalation at a flow rate of 4L/min. Check every half hour. If the patients breathing is less than 20 beats per minute, pulse is less than 120 beats per minute, oxyge
Sponsors
General Hospital of Xizang Military Command of the Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Participants enter high-altitude areas (above 3000 meters above sea level) from plain areas (below 200 meters above sea level) within one week; 2. Participants need to live, work, or engage in high-intensity physical activities in high-altitude environments and have a need for high-altitude adaptation; 3. No serious heart, lung, circulatory, or nervous system diseases; 4. Within the age range of 18 to 65 years old; 5. Participants need to understand the research purpose, process, and potential risks, be willing to participate in the research and practice of high-altitude ladder deoxygenation therapy, and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Serious illness: The candidate suffers from severe heart, lung, or circulatory system diseases and cannot withstand the physiological challenges brought by high-altitude stepwise deoxygenation therapy; 2. Pregnant women or participants with severe psychological disorders; 3. Having traveled to or resided in the plateau for a long time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preliminary habituation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygen consumption;High altitude sickness symptom score;Incidence of severe acute altitude sickness;Incidence of acute altitude sickness; | — |
Countries
China
Contacts
Public ContactBowen Wang
General Hospital of Xizang Military Command of the Chinese People's Liberation Army
Outcome results
None listed