gastric cancer
Conditions
Interventions
SLNB group:Patients with early-stage gastric cancer who are evaluated by gastroscopy and endoscopic ultrasound before surgery should undergo sentinel lymph node dissection at the same time as ESD in t
If positive, standard radical gastrectomy is added.
Patients with pathological diagnosis of off-label after ESD surgery underwent sentinel lymph node dissection within 1 month after ESD
If sentinel lymph nodes are negative, no further lymph node dissection is required
If positive, standard radical gastrectomy is added.
control group:Radical gastrectomy is performed directly for off-label early-stage gastric cancer.
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age>=18 years; 2. Endoscopic or/and pathological diagnosis of early gastric cancer (T1b) beyond ESD indications; 3. Preoperative imaging examinations (such as endoscopic ultrasound, CT, etc.) showed no distant metastases, and the clinical stage was cN0; or by multidisciplinary collaboration (MDT) to discuss the tendency of enlarged lymph nodes around the stomach to be non-metastatic lymph nodes; 4. Patient's informed consent.
Exclusion criteria
Exclusion criteria: 1.History of previous gastric cancer, neoadjuvant therapy or adjuvant therapy; 2. The depth of the lesion exceeds the submucosa; 3. Lymph node metastases or distant metastases on imaging examination; 4.History of other malignant tumors and anti-tumor therapy; 5.Inability to tolerate surgery or presence of contraindications to surgery; 6. Patient does not consent to sentinel lymph node dissection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year disease free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| 5-year disease free survival; | — |
Countries
China
Contacts
Public ContactRong long
Peking University First Hospital
Outcome results
None listed