Skip to content

A real-world study of the efficacy and safety of a bevacizumab-based combination dosing model applied in the treatment of solid tumors

A real-world study of the efficacy and safety of a bevacizumab-based combination dosing model applied in the treatment of solid tumors

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105527
Enrollment
Unknown
Registered
2025-07-04
Start date
2025-07-15
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Solid tumor

Interventions

Observation Group:None

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >=18 years old, gender is not limited; 2.Patients with solid tumors diagnosed by histology or pathology, including but not limited to lung cancer, colorectal cancer and liver cancer; 3.ECOG PS score: 0-3; 4.At least one measurable lesion (according to RECIST 1.1 criteria); 5.Patients treated after January 1, 2023 with two or more cycles of bevacizumab combination regimen;

Exclusion criteria

Exclusion criteria: 1.Persons with proven hypersensitivity to bevacizumab and its excipients; 2.Pregnant or lactating women; 3.Persons who, in the judgment of the investigator, have other factors that make them unsuitable for inclusion in this study;

Design outcomes

Primary

MeasureTime frame
drug-related AEs;abnormal laboratory test values;serious adverse events (SAEs);Incidence and severity of adverse events (AEs);

Secondary

MeasureTime frame
(progression-free survival;PFS);(Objective Response Rate;ORR);(Disease Control Rate;DCR);

Countries

China

Contacts

Public ContactWang Xin

The First Affiliated Hospital of Zhengzhou University

wxgoal@163.com+86 371 66295941

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026