Diseases that require craniotomy surgery
Conditions
Interventions
Intravenous analgesia group:No scalp nerve block is performed, traditional anesthesia is received, and a standardized anesthesia regimen is performed, which includes target controlled infusion of prop
Ropivacaine group:Targeted infusion of propofol 3-4 ug/ml, fentanyl 2-3 ug/kg iv, and cisatracurium 0.2mg/kg were used for anesthesia induction. After anesthesia induction, 0.33% ropivacaine was used
Bupivacaine liposome scalp nerve block group:Targeted infusion of propofol 3-4 ug/ml, fentanyl 2-3 ug/kg iv, and cisatracurium 0.2mg/kg were used for anesthesia induction. After anesthesia induction,
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adult patients between the ages of 18 and 60 who underwent craniotomy; 2. ASA Levels I–III.
Exclusion criteria
Exclusion criteria: 1. Glasgow Coma Scale (GCS) less than 15 points; 2. Allergy to local anesthetics; 3. Contraindications to scalp nerve block; 4. Receiving long-term analgesia or corticosteroid therapy; 5. Opioid tolerance (defined as >30 mg morphine equivalent per day taken by the patient); 6.BMI> 30kg/m^2; 7. Presence of liver and kidney dysfunction and severe cardiopulmonary diseases; 8. Patients who are not cooperative or unwilling to enroll.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Use of analgesic drugs;Demographic data; | — |
Countries
China
Contacts
Public ContactLai Jian
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed