Nervous system disease
Conditions
Interventions
The dexmedetomidine group:Administering dexmedetomidine by infusion before anesthesia induction
Sponsors
Liuzhou Workers' Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Age: between 18 and 55 years old, gender not restricted; 2. ASA I-II grade, BIM 20-35 kg/m^2 3. Patients requiring surgery anesthesia with dexmedetomidine; 4. Voluntary participation in this study and signing the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffering from severe liver or kidney dysfunction (liver function classified as Child-Pugh grade C, creatinine clearance rate < 30 ml/min); 2. Having severe cardiovascular diseases (such as unstable angina pectoris, acute phase of myocardial infarction, severe heart failure, etc.); patients with sinus bradycardia or atrioventricular block; 3. Having a history of mental illness or cognitive dysfunction and unable to cooperate in completing the relevant assessment; 4. Allergic to dexmedetomidine or its excipients; 5. Having used dexmedetomidine recently (within 3 months) or using drugs that may affect the metabolism of dexmedetomidine or have interactions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gene target; | — |
Countries
China
Contacts
Public ContactZhang Yanzhuo
Liuzhou Workers' Hospital
Outcome results
None listed