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Research on Key Technologies of Plasma Cell-Free DNA Fragmentation Omics Features in Early Diagnosis of Gastric Cancer

Research on Key Technologies of Plasma Cell-Free DNA Fragmentation Omics Features in Early Diagnosis of Gastric Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105485
Enrollment
Unknown
Registered
2025-07-04
Start date
2024-01-30
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Gold Standard:Pathological results serve as the gold standard
Index test:Low-depth whole-genome sequencing

Sponsors

Suzhou Xiangcheng People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed with gastric cancer; 2. Age 18 – 75 years old; 3. Blood samples can be provided for cfDNA testing; 4. Voluntarily participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Suffering from severe hepatic and renal insufficiency, hematologic diseases, or other diseases that may affect cfDNA levels; 2. Received chemotherapy, radiotherapy, blood transfusion or other treatments that may affect cfDNA levels within the past 3 months; 3. Unable to provide qualified blood samples; 4. Combined with other malignant tumors (within 5 years) or active infection.

Design outcomes

Primary

MeasureTime frame
cfDNA fragmentomics features;Model performance;

Secondary

MeasureTime frame
Clinicopathological characteristics;

Countries

China

Contacts

Public ContactLian Lian

Suzhou Xiangcheng People's Hospital

dr_lianlian@163.com+86 512 6957 1813

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026