Intestinal flora
Conditions
Interventions
FMT Group:FMT capsule delivery
Bifidobacterium Triplex Capsules:Bifidobacterium triplex capsule administration
Sponsors
Shenzhen People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. 18-65 years old patients with dysbiosis (based on the results of drug sensitivity testing in our hospital or a tertiary hospital); 2. patients with dysbiosis should meet one of the following conditions: (1) the patient's clinical symptoms of refractory diarrhea; (2) the patient is not effective in the treatment of existing means of treatment or the effect is not obvious (the effect is defined as the continuation of diarrhea after the use of the drug); (3) able to be administered through the jejunum tube; 3. The subject and family members ( or guardians) fully read, understood and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.patients with extremely severe disease and expected to die within 48 hours; 2. patients with non-intestinal dysbiosis; 3. patients with severe dysbiosis and gastrointestinal bleeding;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness in curing diarrhea symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory indicators;Immunity indicators; | — |
Countries
China
Contacts
Public ContactLiu Xueyan
Shenzhen People's Hospital
Outcome results
None listed