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Enhanced vs. Conventional Brain-Computer Interface for Stroke Hand Rehabilitation: A Randomized Trial

Enhanced vs. Conventional Brain-Computer Interface for Stroke Hand Rehabilitation: A Randomized Trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105454
Enrollment
Unknown
Registered
2025-07-03
Start date
2025-04-07
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hand dysfunction after stroke

Interventions

Enhanced EEG-BCI group:Brain-computer interface
BCI-TMS group:Brain-computer interface and repeat transcranial magnetic stimulation

Sponsors

Shanghai Fifth Peoople's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. First stroke; 2. Unilateral subcortical injury; 3. The stroke was confirmed by computed tomography (CT) or MRI, and the diagnosis was consistent with the consensus of the Diagnostic Essentials of Various Major Cerebrovascular Diseases in China 2019 formulated by the Cerebrovascular Epidemiology Group of the Branch of Neurology of the Chinese Medical Association; 4. Onset of more than 2 weeks, within 6 months; 5. There were motor dysfunction of the upper limb and hand, and the motor function score of the wrist and hand on the Fugl-Meyer scale was = 25 points.

Exclusion criteria

Exclusion criteria: 1. Patients with serious heart, lung, liver, kidney and other important organ failure in the past, uncontrolled hypertension, arrhythmia, severe coronary heart disease, diabetes complications and poor control; 2. Have a history of seizures or a family history of epilepsy; 3. Intracranial or external metal; 4. The body is equipped with medical instruments, such as cardiac pacemakers, drug pumps, etc. 5. Can not complete the basic course of treatment, poor compliance; 6. Pregnant women; 7. Recent participants in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Fugl-meyer rating;

Secondary

MeasureTime frame
ERD/ERS/ERSP/LI;Coh;Plv;Ppc;Psi;Wpli;Modified Ashworth Scale, MAS;Barthel index;

Countries

China

Contacts

Public ContactDing Ling

Shanghai Fifth Peoople's Hospital

tydingling@163.com+86 21 68035705

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026