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Blood biomarkers to predict complications and outcomes in patients with acute ischemic stroke

Plasma differential inflammatory factors and stroke complications and outcomes

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105450
Enrollment
Unknown
Registered
2025-07-03
Start date
2024-08-01
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischemic stroke

Interventions

Sponsors

Suzhou Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Acute ischemic stroke confirmed with magnetic resonance imaging or computed tomography; 2.Age of 18 years or older; 3.Admission within 7 days of symptom onset;

Exclusion criteria

Exclusion criteria: 1.Active infection within 2 weeks before admission (for the outcome of stroke-associated infection); 2.Duration of hospitalization = 2 days (for the outcome of stroke-associated infection); 3.History of depression, premorbid cognitive decline, and other neuropsychiatric disorders (for the outcomes of post-stroke depression and post-stroke cognitive impairment); 4.Communication problems due to aphasia, severe dysarthria, disturbance of understanding or consciousness (for the outcomes of post-stroke depression and post-stroke cognitive impairment); 5.Pre-stroke modified Rankin scale score of >2 (for the outcome of adverse clinical outcomes after ischemic stroke); 6.Ongoing cancer treatment or use of immunosuppressant or immunomodulator (for the outcomes of stroke-associated infection, post-stroke depression, post-stroke cognitive impairment and adverse clinical outcomes after ischemic stroke); 7.Unable to complete the follow-up (for the outcomes of stroke-associated infection, post-stroke depression, post-stroke cognitive impairment and adverse clinical outcomes after ischemic stroke);

Design outcomes

Primary

MeasureTime frame
post-stroke cognitive impairment;adverse clinical outcomes after ischemic stroke;stroke-associated infection;post-stroke depression;

Countries

China

Contacts

Public ContactXing Jin

Suzhou Municipal Hospital

xing_jin@njmu.edu.cn+86 512 6236 4312

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026