Autism Spectrum Disorder
Conditions
Interventions
tDCS+ combined with rTMS+ :On the basis of behavioral training therapy, tDCS combined with rTMS therapy was used
tDCS+ combined with rTMS-:On the basis of behavioral training therapy, tDCS combined with rTMS-therapy was used
tDCS- combined with rTMS+:On the basis of behavioral training therapy, tDCS-combined with rTMS therapy was used
tDCS- combined with rTMS-:On the basis of behavioral training therapy, tDCS- combined with rTMS- therapy was used
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 2-12 years old; 2. Meet the DSM-5-based diagnostic criteria for ASD and confirmed by the Autism Diagnostic Observation Program Version 2 (ADOS-2); 3. Receiving behavioral rehabilitation therapy.
Exclusion criteria
Exclusion criteria: 1.With a history of epileptic seizures or epilepsy. 2. There is evidence of significant epileptiform activity on the electroencephalogram (EEG). 3. There is a history of severe (traumatic) brain injury. 4. Those with skull defects or unopened fontanelles. 5. Coexisting severe neurological or mental disorders. 6. Those with cochlear implants. 7. Those with metal foreign objects placed near the stimulation coil inside the skull. 8. Implantable devices: equipped with built-in pulse generators, pacemakers, implantable drug pumps, implantable defibrillators and implantable nerve stimulators, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total score of the Autism Treatment Evaluation Checklist (ATEC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Griffiths Neurodevelopmental Assessment Gross Quotient and/or Sub-test developmental Quotient (2-6 years old);Wechsler Intelligence Test Total IQ and/or sub-test scores (6-12 years old);The total score and/or subscale scores of the Infantile - Junior High School Student Social Life Ability Scale (S-M Scale);Total score and/or sub-test score of DN: CAS Cognitive Assessment System (6-12 years old);The total score and/or subscale scores of the Social Responsiveness Scale (SRS) (aged 6-12);The total score and/or subscale score of the Autism Behavior Checklist (ABC);The total score of the Childhood Autism Rating Scale (CARS);The total score and/or subscale scores of the Child Behavior Checklist (CBCL);The total score and/or subscale scores of the Children's Sleep Habits Questionnaire (CSHQ);Changes in near-infrared resting-state brain functional connectivity;The changes of ERP latency and amplitude; | — |
Countries
China
Contacts
Public ContactDong Hanyu
The First Hospital of Jilin University
Outcome results
None listed