The effect of amino acid peritoneal dialysis solution on residual renal function in peritoneal dialysis patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500105428

Enrollment

Unknown

Registered

2025-07-03

Start date

2025-10-01

Completion date

Unknown

Last updated

2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage renal disease

Interventions

Test group:Use 1-2 bags of amino acid peritoneal dialysis solution daily for 24 consecutive months.

Pairing group:Pairing was carried out according to the patients gender, age, serum albumin, baseline residual renal function, transport characteristics, diabetes and other complications

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. 18 to 70 years old, regardless of gender; 2. Stable peritoneal dialysis treatment for PD patients for more than 3 months; 3. Weekly total K t/V>1.7; 4. Urine output>200m/day; 5. The binding capacity of carbon dioxide is greater than 22mmol/L.

Exclusion criteria

Exclusion criteria: 1. Peritonitis has occurred within the past 3 months; 2. Contraindications for amino acid peritoneal dialysis fluid; 3. Received a kidney transplant during the study period.

Design outcomes

Primary

Measure	Time frame
Residual renal function;eGFR;	—

Secondary

Measure	Time frame
blood biochemical;PET;Ca125;	—

Countries

China

Contacts

Public ContactZhong Hui

West China Hospital, Sichuan University

zhonghui39@126.com+86 189 8060 0000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026