Acute-on-chronic liver failure
Conditions
Interventions
Artificial liver treatment Group 1 (Prospective cohort):None
Artificial liver treatment Group 2 (Retrospective cohort):None
Sponsors
Ganzhou Fifth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old; 2. According to the COSSH diagnostic criteria of the Chinese Guidelines for the Diagnosis and Treatment of Liver Failure (2024 Edition), patients diagnosed with hepatitis B-related ACLF: total bilirubin >=12 mg/dL (205 µmol/L) and INR>=1.5 were diagnosed with acute liver failure of hepatitis B; And artificial liver treatment was performed (for prospective enrolled patients who did not receive artificial liver treatment in other hospitals before enrollment).
Exclusion criteria
Exclusion criteria: 1. Presence of any organ tumors; 2. Have a history of organ transplantation; 3. Patients who are not infected with HBV; 4. Incomplete 90-day follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Case fatality rate;AIC/BIC;AUC;Model calibration evaluation;Evaluation of model clinical applicability; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of artificial liver treatments;Incidence of complications; | — |
Countries
China
Contacts
Public ContactLuo Yingmin
Ganzhou Fifth People's Hospital
Outcome results
None listed