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Screening and Validation of Novel Targets for HPV Therapeutic Vaccines Based on Host-Virus Dynamic Interaction Mechanisms in population based cohorts

Screening and Validation of Novel Targets for HPV Therapeutic Vaccines Based on Host-Virus Dynamic Interaction Mechanisms in population based cohorts

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105423
Enrollment
Unknown
Registered
2025-07-03
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical cancer

Interventions

Observation Group:None

Sponsors

West China School of Public Health, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
21 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age 21 years or older, with an intact cervix; 2. Voluntarily sign the informed consent form, agreeing to provide peripheral blood, cervical exfoliated cells, and cervical tissue samples for this study; 3. No clinical symptoms suggestive of pregnancy and not currently lactating; 4. No history of cervical surgery, and able to complete the entire colposcopy procedure.

Exclusion criteria

Exclusion criteria: 1. HIV or Systemic Lupus Erythematosus (SLE) positive test result; 2. Diagnosed with coagulation disorders, thrombocytopenia, or currently receiving anticoagulant therapy, or taking medications/foods that inhibit platelet aggregation and blood clotting; 3. Undergoing long-term steroid or immunosuppressive therapy; 4. Vaginal douching or use of intravaginal medications (e.g., contraceptive creams) within 3 days prior to examination; 5. Sexual intercourse or application of acetic acid/iodine solution within 24 hours prior to examination; 6. Physical or mental inability to undergo routine cervical cancer screening.

Design outcomes

Primary

MeasureTime frame
Human Papillomavirus;Human Leukocyte Antigen;

Countries

China

Contacts

Public ContactLi Jing

West China School of Public Health / West China Fourth Hospital, Sichuan University

lijingwcph@scu.edu.cn+86 132 4022 5540

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026