Parkinson's disease
Conditions
Interventions
Intervention group:The intervention group orally took 5 capsules (0.5g/ capsule) of gel candy or placebo each time, taken at least 1 hour before meals or at least 2 hours after meals, twice a day (a
control group:The control group orally took 5 capsules (0.5g/ capsule) of placebo each time, taken at least 1 hour before meals or at least 2 hours after meals, twice a day (a total of 5g/ day), for
Sponsors
Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age: 40 to 75 years old, gender not limited (including 40 and 75 years old); 2. Patients diagnosed with Parkinson's disease according to the "Diagnostic Criteria for Parkinson's Disease in China (2016 Edition)"; 3. MMSE scale score >= 26 points; 4. The Hoehn and Yahr scale score is level 1 to 3; 5. Understand and abide by the trial process, participate voluntarily, and sign the informed consent form (the informed consent form shall be signed voluntarily by the individual or their legal representative).
Exclusion criteria
Exclusion criteria: 1. Clinical manifestations are atypical Parkinson's syndrome or there is a history of atypical Parkinson's syndrome; 2. Patients with other neurological complications, such as dementia, epilepsy, cerebral infarction, cerebral hemorrhage, brain trauma, craniocerebral tumors, and a history of craniocerebral surgery, etc. 3. Diagnose patients with anxiety, depression, mental illness, alcohol dependence, drug dependence, etc 4. Mini-Mental State Assessment (MMSE)<=24; 5. Pregnant women or those who are breastfeeding; 6. Those who are allergic to the test drug or the excipients of the research drug (mannitol, hydroxypropyl cellulose, cross-linked polyretinone, talcum powder, sodium bicarbonate, magnesium stearate, copolymer of methacrylate and ethyl acrylate, triethyl citrate, titanium dioxide).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Part III Scoring of the UPDRS Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hoehn and Yahr Scale;The frequency and extent of the occurrence of the "switching phenomenon"; | — |
Countries
China
Contacts
Public ContactLi Zhenshui
Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed