None
Conditions
Interventions
Fospropofol disodium group (F):Fospropofol disodium group
Fospropofol disodium + propofol group (FP):Fospropofol disodium + propofol group
Sponsors
The First People’s Hospital of Jingzhou
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Gender is not limited, age 65-80 years old; 2.BMI=19~28 kg /m2; 3.ASA class II or III; 4.Peration length <= 30 min; 5.Complete and accurate clinical data; 6.Patients and family members are fully aware of the process of this study, and are willing to sign the informed consent form and comply with the order in strict accordance with the requirements.
Exclusion criteria
Exclusion criteria: 1.Hypersensitivity to intravenous anesthetics or analgesics; 2.Psychiatric or neurological disorders; 3.Asthma exacerbation period; 4.Long-term application of narcotic sedative and analgesic medications; 5.Severe hepatic or renal impairment; 6.Difficult airway; 7.Recent history of upper respiratory tract infections; 8.History of alcohol or drug abuse; 9. Participated in other drug clinical trials as a subject in the past 3 months. 10. Patients who refused to participate in the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation success;Onset of action; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to loss of eyelash reflex;HR at different time points;Postoperative adverse reaction stituation;Additional dose of propofol;RR at different time points;MAP at different time points;SpO2 at different time points;Time to awakening,;Narcotrend values at different time points;Time to discharge; | — |
Countries
China
Contacts
Public ContactXia Rui
The First People’s Hospital of Jingzhou
Outcome results
None listed