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Low-Dose Rocuronium as an Adjuvant to Remifentanil for Laryngeal Mask Airway-Assisted Flexible Fiberoptic Bronchoscopy in children

Low-Dose Rocuronium as an Adjuvant to Remifentanil for Laryngeal Mask Airway-Assisted Flexible Fiberoptic Bronchoscopy in children: a Randomized Placebo-Controlled Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105407
Enrollment
Unknown
Registered
2025-07-03
Start date
2025-11-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The anesthesia plan for fiberoptic bronchoscopy

Interventions

rocuronium group:Intravenous injection of 0.3mg/kg rocuronium
normal saline group:Intravenous injection of the same volume of normal saline

Sponsors

Children's Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1.aged between 1 and 6 years; 2.American Society of Anesthesiologists (ASA) physical status of ? or ?; 3.body mass index (BMI) between 14 and 18kg/m^2; 4.being scheduled to undergo FFB under anesthesia for the following indications: pneumonia, broncho-alveolar lavage (BAL), airway mucosal biopsy or foreign body removal.

Exclusion criteria

Exclusion criteria: 1.pulse oxygen saturation (SpO2) <90% prior to FFB; 2.preoperative acute exacerbations of cough; 3.history of allergy to related medications; 4.contraindications for the use of muscle relaxants include conditions such as mediastinal tumors; 5.hypertrophy of the tonsils and adenoids may potentially affect the proper placement of the laryngeal mask; 6.second- or third-degree heart block; 7.history of asthma;

Design outcomes

Primary

MeasureTime frame
the frequency of coughing episodes during the FFB operation period (from bronchoscope insertion to its removal);

Secondary

MeasureTime frame
hemodynamic changes;satisfaction scores of anesthesiologist;satisfaction scores of patient;cumulative remifentanil dosage;The failure rate of flexible fibreoptic bronchoscopy operation;satisfaction scores of bronchoscopist;procedure time;adverse events;cough scores in the PACU;discharge time;

Countries

China

Contacts

Public ContactXu Shangxian

Children's Hospital of Soochow University

xushangxian0321@163.com+86 512 8069 1319

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 9, 2026