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Short-term effects of 0.05% atropine solution on retina and choroid

Short-term effects of 0.05% atropine solution on retina and choroid

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105401
Enrollment
Unknown
Registered
2025-07-02
Start date
2025-07-02
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia

Interventions

intervention group:Self-controlled trial, 0.05% atropine eye solution was used in both eyes on the second day of the trial.

Sponsors

Changsha Aier Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Chinese nationality (yellow race); 2. Healthy people over 18 years old with mild and moderate myopia (equivalent spherical >=-6.00DS, axial length <=26.00mm); 3. Use a standard logarithmic visual acuity chart with a binocular best corrected visual acuity (BCVA) of not less than 1.0 (0.0 logMAR).

Exclusion criteria

Exclusion criteria: 1. Active, progressive eye disease; 2. Combined with other systemic diseases that may affect visual function or refractive status; 3. Systemic diseases, such as cervical spondylosis, lumbar spondylosis, hypertension and diabetes and other cardiovascular diseases; 4. Previous history of eye surgery; 5. Other conditions that the investigator considers unsuitable for participation in the study.

Design outcomes

Primary

MeasureTime frame
Choroidal thickness;choroidal blood flow;a wave amplitude (ERG );b wave amplitude (ERG );retinal thickness;

Countries

China

Contacts

Public ContactXu Qinglin

Aier eye hospital group

460897699@qq.com+86 186 8483 9647

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026