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A case-control study on the potential correlation between gut microbiota and oral cancer

A case-control study on the potential correlation between gut microbiota and oral cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105398
Enrollment
Unknown
Registered
2025-07-02
Start date
2025-07-15
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral cancer

Interventions

No oral cancer group:None
Oral cancer group:None

Sponsors

The Second Affiliated Hospital of the Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Case group: 1. Age>= 18 years old, = 18 years old, < 75 years old, gender is not limited; 2. Patients who need to be extracted only for wisdom teeth and extra teeth, orthodontics, implant restoration, removable dentures, fixed dentures restoration, or those who have no oral diseases; 3. No benign or malignant tumors; 4. The whole body condition is acceptable, and there are no serious diseases of important organs such as liver and kidney; 5. Agree to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: Case group 1. Comorbid with primary immune system disease, primary hematologic disease or primary malnutrition; 2. Taking Chinese medicine or other drugs related to immune function and blood system; 3. Previous tumor treatment for head and neck cancer, such as radiotherapy, chemotherapy, immunotherapy, and targeted therapy; 4. Inability to comply with experimental research procedures due to geographical, familial, social or psychological reasons; 5. Pregnant women. Control group 1. Suffering from primary immune system disease, primary hematologic disease, or primary malnutrition; 2. Taking Chinese medicine or other drugs related to immune function and blood system; 3. Previous tumor treatment for head and neck cancer, such as radiotherapy, chemotherapy, immunotherapy, and targeted therapy; 4. Inability to comply with experimental research procedures due to geographical, familial, social or psychological reasons; 5. Pregnant women.

Design outcomes

Primary

MeasureTime frame
Intestinal flora;Circulating metabolite level;

Countries

China

Contacts

Public ContactHaitao He

The Second Affiliated Hospital of the Army Medical University

Jack_paul223@sina.com+86 13508369133

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026