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Clinical study of low-dose rocuronium bromide assisted by esketamine in rapid sequential induction of tracheal intubation in children

Clinical study of low-dose rocuronium bromide assisted by esketamine in rapid sequential induction of tracheal intubation in children

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105378
Enrollment
Unknown
Registered
2025-07-02
Start date
2025-07-10
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enlarged tonsils and/or adenoids

Interventions

AS:Subjects will be administered esketamine 0.5 mg/kg intravenously.
R:The subjects will receive intravenous injection of physiological saline.

Sponsors

Ganzhou People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 12 Years

Inclusion criteria

Inclusion criteria: Age range: 4-12 years old, gender not limited, ASA grade I-II, preoperative assessment shows no suspected difficult airway, no neurological or muscular system dysfunction, and no contraindications to conventional anesthesia.

Exclusion criteria

Exclusion criteria: Within 2 weeks, the patient has a history of upper respiratory tract infection, significant abnormalities in heart, liver, and kidney function, and their family members do not agree to cooperate. The patient's body weight exceeds 25% of the normal value.

Design outcomes

Primary

MeasureTime frame
Evaluation of tracheal intubation conditions at 90s after rocuronium bromide injection in two groups of children;

Secondary

MeasureTime frame
The time from the end of anesthesia to extubation was compared between the two groups of children.;

Countries

China

Contacts

Public ContactHuang Huimin

Ganzhou People's Hospital

251130558@qq.com+86 183 7046 4954

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026