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Comparison of norepinephrine and phenylephrine on maternal core temperature during caesarean section: a randomized, double-blind, non-inferiority trial

Comparison of norepinephrine and phenylephrine on maternal core temperature during caesarean section: a randomized, double-blind, non-inferiority trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105375
Enrollment
Unknown
Registered
2025-07-02
Start date
2025-07-04
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maternal hypothermia

Interventions

Sponsors

The Second People's Hospital of Hefei
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Pregnant women aged between 18 and 40 years old; 2.ASA classification I-II; 3. Single term pregnancy; 4. Undergo spinal anesthesia to perform cesarean section, and collection of umbilical cord blood and maternal venous blood during the perioperative period; 5. Agree to participate in this study;

Exclusion criteria

Exclusion criteria: 1. Unable or refusing to sign the informed consent form; 2. Those who are allergic to norepinephrine or phenylephrine or are not suitable for use; 3. Those with known abnormal fetal development; 4. Those who are accompanied by severe heart, brain, liver, and kidney diseases; 5. Those who are currently using monoamine oxidase inhibitors or tricyclic antidepressants; 6. Those who have contraindications to intrathecal anesthesia; 7. Those who are unable to communicate and cooperate.

Design outcomes

Primary

MeasureTime frame
Core body temperature ;

Secondary

MeasureTime frame
Incidence of shivering;Incidence of hypothermia;Thermal comfort score;Incidence of hypotension;Incidence of bradycardia;

Countries

China

Contacts

Public ContactJinfeng Bao

The Second People's Hospital of Hefei

252295142@qq.com+86 551 6296 5094

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026