Obstructive sleep apnea syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: OSA Group: 1. Age 3-18 years old; 2. All children were diagnosed with OSA (confirmed by polysomnography) before surgery; 3. The child had OSA symptoms such as sleep snoring, mouth breathing, and nocturnal awakening; 4. Diagnosis of tonsillar hypertrophy and adenoid hypertrophy; 5. All family members of the affected children signed the informed consent form. Control group: 1. Age 3-18 years old; 2. The child has no obvious inflammatory, infectious or tumor diseases in the preoperative diagnosis, such as congenital ear attachment, sensorineural hearing loss, small masses on the body surface and other diseases; 3. The child had no obvious OSA symptoms; 4. All family members of the child signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Respiratory tract infection (within 2 weeks) in the short period before surgery; 2. The child has obvious neurological developmental disorders, congenital developmental abnormalities, etc.; 3. The child has a hematologic disorder; 4. The child has contraindications to general anesthesia; 5. History of malignant tumor disease in the child; 6. The family members of the children do not agree to be enrolled in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The presence of obstructive sleep apnea syndrome;The severity of obstructive sleep apnea syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative bleeding;Postoperative fever;Postoperative pain; | — |
Countries
China
Contacts
Shanghai Children's Hospital