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Clinical Cohort Study on Early Diagnostic Biomarkers for Sepsis - Second Cohort (Sepsis Marker Early Diagnosis-2 [SepMeD-2])

Clinical Cohort Study on Early Diagnostic Biomarkers for Sepsis - Second Cohort (Sepsis Marker Early Diagnosis-2 [SepMeD-2])

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105360
Enrollment
Unknown
Registered
2025-07-02
Start date
2025-07-15
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Sepsis group:None

Sponsors

Yuebei People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years?; 2.?? High-risk population with suspected sepsis (meeting any one of the following criteria):?? ??(1) Evidence of infection?? (positive microbiological culture); ??(2) Systemic inflammatory response?? (at least two of the following: Body temperature >38°C or 90 beats per minute; Respiratory rate >20 breaths per minute or PaCO2 12×10?/L or 10%); ??(3) Organ dysfunction?? (SOFA score >=2). 3. Within 12 hours of admission to the emergency department (ED) or ICU?;

Exclusion criteria

Exclusion criteria: 1. Patients with cancer?; 2. Patients with blood system diseases?; 3. HIV-seropositive individuals?; 4. Patients with end-stage liver and/or kidney failure?; 5.?? Patients with autoimmune disorders?; 6. Patients who received hormonal therapy or immunosuppressants in the last 6 months?; 7.?? Patients with a history of organ transplantation, including bone marrow, liver, kidney, or lung transplants?; 8. Participants with missing or incomplete study data?; 9. Patients diagnosed with sepsis at the time of initial medical presentation?;

Design outcomes

Primary

MeasureTime frame
Blood Markers and Related Test Indicators;

Countries

China

Contacts

Public ContactZhao Pingsen

Yuebei People’s Hospital

zhaopingsen01@163.com+86 13332876639

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026