Full-Left-Full-Right Split Liver Transplantation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Donor enrollment criteria Basic conditions: 1. Donor liver assessment is suitable for split transplantation and donor age = 18 years of age. Diagnosed with end-stage liver disease after clinical evaluation, meeting the indications for liver transplantation. Intended to undergo complete left and right hemiliver split liver transplantation (FR/FLSLT); 2. No obvious contraindications; 3. Other requirements: signed informed consent form and committed to complete at least 3 years of follow-up.
Exclusion criteria
Exclusion criteria: Recipient Exclusion Criteria 1.Presence of concurrent organ failure in other vital organs(such as heart,lung,kidney,etc.),with an expectation of intolerance to liver transplantation surgery; 2.Active infections that cannot be effectively controlled; 3. Malignancies exceeding the acceptable range for transplantation; 4.Undergoing multi-organ transplantation; 5.Severe psychiatric disorders or poor compliance that would preclude effective postoperative management.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient survival rate;Liver function(ALT,AST,Total bilirubin);Hepatic artery, hepatic vein, portal vein and biliary stenosis situation;Hepatic artery, hepatic vein, portal vein thrombosis status;Hepatic artery, hepatic vein, portal vein flow velocity status;Hepatic artery, hepatic vein, portal vein and biliary stenosis situation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine ;Blood coagulation function;Kidney function;Electrolyte;Biliary tract condition;Lung condition;Cardiovascular status;Blood concentration of antirejection drugs; | — |
Countries
China
Contacts
Shulan(Hangzhou)Hospital