Lung cancer
Conditions
Interventions
Sponsors
Zhejiang cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. According to clinical imaging evaluation, patients with stage IIA-IIIB non-small cell lung cancer who are expected to undergo complete surgical resection (based on the 8th edition AJCC TNM staging); 2. If the pathological type is adenocarcinoma and there are no EGFR/ALK sensitive mutations; 3. When signing the informed consent form, the age is equal to or greater than 18 years old and less than or equal to 75 years old; 4. The patient's ECOG score ranges from 0 to 1; 5. The functional reserve of important organs meets the requirements of chemotherapy, immunotherapy, and surgery; According to the RESIST v1.1 standard, there are target lesions that can be measured through imaging examinations.
Exclusion criteria
Exclusion criteria: 1. History of other malignant tumors; 2. Pathological diagnosis of small cell lung cancer before treatment; 3. Adenocarcinoma patients have EGFR/ALK sensitive mutations; 4. Previously received chemotherapy, radiation therapy, or other anti-tumor treatments; 5. Have received systemic immune stimulant or systemic immune suppressant treatment within 4 weeks before the first administration (excluding inhaled or locally administered steroid hormones); 6. Existence of autoimmune related diseases; 7. Known or suspected interstitial pneumonia; 8. Suffering from severe cardiovascular and cerebrovascular diseases; 9. There are significant bleeding events or arteriovenous thrombosis events within 3 months before the first administration; 10. HIV positive or active hepatitis B/C virus; 11. Other researchers believe that it is not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathological remission rate;Traditional Chinese Medicine Syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| CT;Pulmonary function;Heart function;Blood routine;Urinalysis;Fecal routine;blood biochemical;blood clotting;Blood Gas Analysis;Tumor markers;NK complete set;Infectious disease examination; | — |
Countries
China
Contacts
Public ContactJian Zeng
Zhejiang cancer hospital
Outcome results
None listed