Parkinson's disease
Conditions
Interventions
Sponsors
Second Affiliated Hospital,School of Medicine,Zhejiang University
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the 2015 International Movement Disorder Association Diagnostic Criteria for Primary Parkinson's Disease; 2. Aged between 30~75 years old; 3. No anti-Parkinson's disease-related drug therapy or stable dose of other types of drug therapy (such as levodopa, dopamine receptor agonists, etc.) within 3 months at the time of initial enrollment; 4. Have lived in the local area for at least 5 years and have a fixed residence; 5. Have not participated in other research projects at present; 6. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who are judged by the investigator to be allergic to the treatment of Parkinson's disease; 2. Pregnant or lactating women; 3. Severe cardiovascular and cerebrovascular diseases or abnormal liver and kidney function, such as cancer, coronary heart disease, myocardial infarction and stroke; 4. Suffering from infectious diseases such as tuberculosis and AIDS or active systemic inflammatory diseases, such as tuberculosis, rheumatoid arthritis, etc.; 5. Patients with severe other neurodegenerative diseases or secondary PD syndrome or atypical PD syndrome; 6. Those who cannot cooperate with the completion of follow-up; 7. Other circumstances that the researcher deems inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MDS-UPDRS ? (MDS Unified-Parkinson Disease Rating Scale) score difference; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the non-motor symptoms; Drug side effect ;Adverse event ; | — |
Countries
China
Contacts
Public ContactZhang Baorong
Second Affiliated Hospital,School of Medicine, Zhejiang University
Outcome results
None listed