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Curative effect of sequential chemotherapy combined with arterial resection in locally advanced pancreatic cancer

Curative effect of sequential chemotherapy combined with arterial resection in locally advanced pancreatic cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105336
Enrollment
Unknown
Registered
2025-07-02
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic cancer

Interventions

Experimental group:Adjuvant chemotherapy followed by radical surgery combined with arterial resection

Sponsors

Beijing Chao-Yang Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18 -80 years old; 2. Expected survival time of more than 6 months; 3. Locally advanced pancreatic cancer on imaging examination (defined using the 2021 NCCN guidelines); 4. Pathological puncture confirmed pancreatic adenocarcinoma; 5. Comprehensive assessment of tumor without distant metastasis; 6. Informed consent of patients and their families under the study protocol.

Exclusion criteria

Exclusion criteria: 1. Less than 4 cycles due to inability to tolerate chemotherapy; 2. After chemotherapy, the evaluation is in line with the timing of surgery, but the surgical treatment is refused for various reasons; 3. Tumor progression after chemotherapy is completed; 4. Postoperative pathological confirmation of non-pancreatic adenocarcinoma; 5. Patients or family members withdraw from the study protocol halfway through for various reasons.

Design outcomes

Primary

MeasureTime frame
Mortality;

Secondary

MeasureTime frame
Recurrence;Perioperative mortality;Tumor progression;Incidence of postoperative complications;

Countries

China

Contacts

Public ContactLang Ren

Beijing Chao-Yang Hospital, Capital Medical University

dr_langren@126.com+86 10 8523 1504

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026