Painless bronchoscopy in children
Conditions
Interventions
Trial Group :Remazolam combined with remifentanil was used for anesthesia
Control group:Propofol combined with remifentanil was used for anesthesia
Sponsors
Boai Hospital of Zhongshan
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age 0~12 years old, gender is not limited; 2. Patients undergoing elective general anesthesia; 3. BMI 18.5~24.9kg/m^2;The child's weight is within two standard deviations of body weight (±2SD) in this age group; 4. ASA Class I or II; Mallampati Class I or II; 5. No contraindications to the use of esketamine, remimazolam, lidocaine, propofol, remifentanil and other drugs; 6. No history of drug abuse.
Exclusion criteria
Exclusion criteria: 1. Children whose parents or guardians do not agree to participate in the study; 2. BMI>=25kg/m^2 or the child's weight exceeds two standard deviations of body weight (±2SD) for the age group; 3. Children with severe heart, liver, kidney and other important organ dysfunction or disease; 4. Children with severe intracranial hypertension, intracranial infection, and intracranial mass lesions; 5. Children with congestive heart failure, shock, respiratory failure or electrolyte disorders; 6. Children with severe mental illness or neurological disease have a history of drug allergy; 7. Severe anemia, coagulation dysfunction, etc.; 8. Children with drug allergies; 9. Children who urgently need emergency surgical treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia (SPO2 < 90%); | — |
Secondary
| Measure | Time frame |
|---|---|
| Success rate of bronchoscopy;Incidence of hypotension;Occurrence of adverse reactions; | — |
Countries
China
Contacts
Public ContactMeiyun Tan
Department of Anesthsiology, Affiliated Boai Hospital of Zhongshan
Outcome results
None listed