Time to full enteral feeding
Conditions
Interventions
Observation Group :breast milk enema
Control Group:Glycerol Diluent Enema
Sponsors
Southwest Medical University Affiliated Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: 1. Low Birth Weight Infant (LBW): Live-born infant with birth weight < 2,500 g 2. Very Low Birth Weight Infant (VLBW): Live-born infant with birth weight < 1,500 g 3. Extremely Low Birth Weight Infant (ELBW): Live-born infant with birth weight < 1,000 g 4. Mother able to provide breast milk 5. Written informed consent obtained from the infant's parents
Exclusion criteria
Exclusion criteria: 1. Presence of severe conditions: Congenital malformations, congenital gastrointestinal anomalies, anorectal malformations, diarrhea, intussusception, necrotizing enterocolitis (NEC), patent ductus arteriosus (PDA), sepsis, neutropenia, or coagulation disorders. 2. Spontaneous passage of meconium within 48 hours after birth.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Full Enteral Feeding Time (FEF) Time to Complete Meconium Evacuation (TCME); | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of Parenteral Nutrition (DPN),Length of Hospital Stay (LOS),Discharge Weight,Complication Incidence: necrotizing enterocolitis (NEC), bowel perforation, secondary neonatal hyperbilirubinemia induced by feeding/enema procedures, feeding intolerance, etc.Post-discharge Outcomes (1-year):Readmission Frequency for feeding-related issues (e.g., malnutrition, gastrointestinal infections),Total Readmission Days; | — |
Countries
China
Contacts
Public ContactZHANG Guoyan
Southwest Medical University Affiliated Hospital
Outcome results
None listed