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Effect of liposomal bupivacaine for intercostal nerve block on chronic postoperative pain following thoracoscopic lung resection: a retrospective cohort study

Effect of liposomal bupivacaine for intercostal nerve block on chronic postoperative pain following thoracoscopic lung resection: a retrospective cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105292
Enrollment
Unknown
Registered
2025-07-01
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thoracoscopic lung surgery

Interventions

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Patients >= 18 years old classified as American Society of Anesthesiologists (ASA) physical status I-III; (2) Undergoing elective thoracoscopic lung surgery; (3) Receiving intercostal nerve blocks applied with liposomal bupivacaine or ropivacaine at the end of the surgery.

Exclusion criteria

Exclusion criteria: (1) had chronic pain before the surgery; (2) had severe preoperative anxiety or depression status on long-term medication; (3) had a history of thoracic surgery; (4) underwent bilateral pulmonary resection or conversion to open surgery; (5) had tumour recurrence or metastasis after surgery; (6) had hepatic disease (Child-Pugh classification C) or renal failure (receiving renal replacement therapy); (7) missing main outcome.

Design outcomes

Primary

MeasureTime frame
the incidence of CPSP at 3 months postoperatively;

Secondary

MeasureTime frame
NRS pain scores at rest at 24 and 48 hours after surgery;The total amount of opioid analgesics within 0-48 h postoperatively;Time to postoperative independent activities;Length of hospital stay;Occurrence of postoperative neuropathic pain at 3 months postoperatively;

Countries

China

Contacts

Public ContactXi-Sheng Shan

The First Affiliated Hospital of Soochow University

xisheng83@sina.com+86 158 9555 1822

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026