The Chronic Refractory Wounds
Conditions
Interventions
Control group:PRP intervention
Experimental group:HPU+PRP combination intervention
Sponsors
The Affiliated Hospital of Southwest Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The wound does not heal for 4 weeks > or the wound has not healed for 4 weeks > regular treatment, or even the wound with an enlarged wound area and no obvious healing tendency; 2. Patients with good compliance and voluntary signing of informed consent; 3. Those whose blood routine, coagulation routine, platelet function and count are normal, and peripheral blood cell fractionation can be performed.
Exclusion criteria
Exclusion criteria: 1. Those who are receiving hormonal or immunosuppressive therapy; 2. Diabetic patients with poor blood sugar control; 3. Serum albumin<30g/L; 4. Patients with coagulation dysfunction; 5. Patients with severe cardiopulmonary insufficiency (FEV1<80%, FVC<80%, FEV1/FVC <70%); 6. Those with malignant tumors or severe autoimmune diseases; 7. Patients with sepsis and sepsis; 8. Those suffering from mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total effective rate of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Negative conversion rate of bacterial culture in wound secretions;Inflammatory response indicators;Pain score;Wound healing rate;Total number of dressing changes;Total healing time;Vancouver scar scale; | — |
Countries
China
Contacts
Public ContactHuang Liheng
The Affiliated Hospital of Southwest Medical University
Outcome results
None listed