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Analysis of Relevant Factors Affecting the Clinical Efficacy and Adverse Reactions of Anlotinib

Analysis of Relevant Factors Affecting the Clinical Efficacy and Adverse Reactions of Anlotinib

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105222
Enrollment
Unknown
Registered
2025-07-01
Start date
2025-07-15
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Observation group:None

Sponsors

Shanghai changhai hosipatal
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age: >=18 years old; 2. Patients with tumors treated with anlotinib (including patients with acinar soft tissue sarcoma, clear cell sarcoma and other advanced soft tissue sarcomas that have progressed or relapsed; Patients with clinically symptomatic or definite disease progression, unresectable locally advanced or metastatic medullary thyroid cancer; Patients with advanced, locally advanced, or metastatic radioiodine-refractory differentiated thyroid cancer); 3. Complete pre-medication laboratory examination related indicators (blood routine, liver enzyme related indicators, etc.); This criterion is used in patients included in the assessment of adverse reactions; Note: If it is a efficacy-related study, it is necessary to additionally meet the requirements of patients with lung cancer with clear pathological and imaging diagnosis, and patients with locally advanced or metastatic lung cancer who have progressed or relapsed after receiving at least 2 types of systemic chemotherapy, including NSCLC and SCLC.

Exclusion criteria

Exclusion criteria: 1. Refusal to sign informed consent; 2. Unable to evaluate ADR and efficacy-related data; 3. Inability to assess medication adherence.

Design outcomes

Primary

MeasureTime frame
SNPs;complete remission;partial remission;stable disease;progressive disease;

Secondary

MeasureTime frame
progress free survival;overall survival;

Countries

China

Contacts

Public ContactWang Zhuo

Shanghai Changhai Hospital

wangzhuo088@163.com+86 138 1839 0863

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026