Internal carotid artery stenosis
Conditions
Interventions
High-Flow Nasal Oxygen Group (Group H):Administration of pure oxygen using a high-flow nasal oxygen (HFNO) device
Face Mask Oxygen Group (Group M):Administration of pure oxygen via face mask
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective internal carotid artery decortication in the Department of Neurosurgery of Xuanwu Hospital; 2. Age> = 18 years old, no restriction on gender 3. Patients with American Society of Anesthesiologists (ASA) grade I.~III.; 4. Good cognitive function and can cooperate with the implementation of the research protocol; 5. Unilateral carotid artery stenosis rate diagnosed by preoperative TCD >=50%; 6. Intraoperative TCD was used to monitor the cerebral blood flow in the middle cerebral artery; 7. Patients who voluntarily signed the "Informed Consent Form of Subjects".
Exclusion criteria
Exclusion criteria: 1. Previous history of nasopharyngeal malformation or surgery; 2. Patients with nasopharyngeal masses and vegetations or a recent history of nasopharyngeal bleeding; 3. Patients with acute nasopharyngeal inflammation; 4. Patients with respiratory failure or CO2 accumulation shown by preoperative arterial blood gas analysis (PaCO2>=45mmHg); 5. Other conditions that are not suitable for HFNO, such as complete upper airway obstruction, basilar skull fracture and nasal bone fracture.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relative velocity of middle cerebral artery blood flow after 10 minutes of oxygen administration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Relative velocity of middle cerebral artery blood flow;Blood pressure;Transcutaneous carbon dioxide monitoring value;Lowest oxygen saturation during oxygen administration;Incidence of subclinical respiratory depression;Incidence of oxygen-related adverse events;Incidence of hyperperfusion syndrome; | — |
Countries
China
Contacts
Public ContactLei Zhao
Xuanwu Hospital of CCMU
Outcome results
None listed