Bronchial asthma
Conditions
Interventions
Group B:Chloroacetylmethacholine excitation test
Group A:The distilled water provocation test
Sponsors
The Second Affiliated hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Applicants must be over 18 years old and under 65 years old. 2. Presence of symptoms suspected of asthma, such as recurrent wheezing, cough, chest tightness, etc. (> 8 weeks). 3. No use of inhaled hormones or discontinuation of > = 4 weeks. 4. Able to understand and comply with the requirements of the study, and willing to sign the informed consent form. 5. Able to complete pulmonary function tests independently. 6. Baseline FEV1 > = 70% predicted and baseline PEF > = 80% predicted.
Exclusion criteria
Exclusion criteria: 1. Have been diagnosed with other types of respiratory diseases (such as chronic obstructive pulmonary disease, tuberculosis, etc.). 2. Recent respiratory tract infection (< 4 weeks). 3. Use of drugs that affect airway responsiveness within the last month. 4. Have severe systemic diseases (such as heart disease, diabetes, etc.). 5. Pregnant or lactating women. 6. Those who are allergic to chlorethethiacholine or distilled water. 7. Those who have serious mental illness and cannot cooperate with the completion of the test. 8. Presence of significant dyspnea or full-lung wheezing. 9. Baseline FEV1 < 60% predicted.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PD20FEV1; | — |
Secondary
| Measure | Time frame |
|---|---|
| FEV1;PEF; | — |
Countries
China
Contacts
Public ContactYiming Zeng
The Second Affiliated hospital of Fujian Medical University
Outcome results
None listed