Tooth loss
Conditions
Interventions
No atrial fibrillation group:None
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Inclusion criteria for atrial fibrillation group: (1) Age 60-90 years old (including 60 and 90 years old); (2)The patient requests dental implant restoration,and the implant surgery is under local anesthesia; (3)The patient has atrial fibrillation and with a standardized treatment duration of >=6 months; (4)The patient participate in the research voluntarily, cooperate with the examination and sign the informed consent form. 2.Inclusion criteria for no atrial fibrillation group: Age 60-90 years old (including 60 and 90 years old); (2)The patient requests dental implant restoration,and the implant surgery is under local anesthesia;(3)No atrial fibrillation;(4) No long-term oral anticoagulant drugs or antiplatelet drugs treatment; (5)The patient participate in the research voluntarily, cooperate with the examination and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.There are obvious oral abscesses, precancerous lesions, fungal infections and pericoronitis of wisdom teeth throughout the mouth; 2.Patients has a history of bleeding during oral surgery; 3.Patients with a history of myocardial infarction or heart failure within 6 months, or cerebrovascular accident within 3 months; 4.Patients who need to take aspirin orally within one year after myocardial infarction; 5.The blood pressure on the day of the operation was >=180/110 mmHg; 6.There are coagulation disorders, thrombocytopenia, hemophilia or significant anemia; 7.Glycated hemoglobin > 10%; 8.Patients has impaired renal function, creatinine clearance rate 10mg per day); 11.Malignant tumors that have not received standardized treatment, or have received standardized treatment for less than five years; 12.Those diagnosed with acquired immunodeficiency syndrome, syphilis and hepatitis B, who have not received standardized treatment and control; 13.Patients with severe cognitive impairment (dementia), schizophrenia, and severe depression.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of peri-implantitis one year after the completion of implant restoration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall safety;The incidence of local bleeding within 2 weeks after implantation surgery;The incidence of implant complications within one year after the completion of implant denture restoration;The incidence of other local safety events within one year after the completion of implant denture restoration;Subjective evaluation of patients within one year after the completion of implant denture restoration;The score results of the cognitive scale within one year after the completion of implant denture restoration.; | — |
Countries
China
Contacts
Public ContactDuohong Zou
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed