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Simulated RCT study of Comparison of Lactated Ringer's Solution and Normal Saline in the Resuscitation Treatment of Acute Pancreatitis

Simulated RCT study of Comparison of Lactated Ringer's Solution and Normal Saline in the Resuscitation Treatment of Acute Pancreatitis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105180
Enrollment
Unknown
Registered
2025-06-30
Start date
2025-02-20
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute pancreatitis

Interventions

Lactate Ringer's group:None

Sponsors

Shanghai Changhai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with mild acute pancreatitis who are screened in the medical record system of the Information Department of Changhai Hospital and meet 2 of the following criteria are eligible: (1) Epigastric pain; (2) serum amylase and/or lipase greater than 3 times the upper limit of normal; (3) Imaging findings consistent with acute pancreatitis (AP). 2. Patients who are using high-dose solutions for fluid resuscitation meet one of the following criteria: (1) There are more than 500ml of infusion records in the medication record; (2) There is a record of infusion greater than 500ml in the prescription.

Exclusion criteria

Exclusion criteria: 1. Includes severe acute pancreatitis as defined by the revised Atlanta classification, NYHA class II heart failure, pulmonary edema, renal insufficiency (Cr > 1.9 mg/dL), and hepatic insufficiency (albumin < 3 mg/dL or history of cirrhosis); 2. Patients with clinical symptoms of hypervolemia, including pulmonary congestion, peripheral swelling and ascites, as well as pregnant patients aged < 18 years.

Design outcomes

Primary

MeasureTime frame
The incidence/scores of SIRS after 24 hours of treatment;

Secondary

MeasureTime frame
The incidence/scores of SIRS after 48 hours of treatment;The incidence/scores of SIRS after 72 hours of treatment;Progression to moderate/severe acute pancreatitis;ICU occupancy;Length of hospital stay;

Countries

China

Contacts

Public ContactHuiyun Zhu

Shanghai Changhai Hospital

zhuhuiyun0205@qq.com+86 150 2692 1681

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026