Postoperative acute pain
Conditions
Interventions
Experimental group:Local infiltration with liposomal bupivacaine and bupivacaine hydrochloride
Control group:Local infiltration with ropivacaine
Sponsors
Department of Anesthesiology, Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age 18 and above; 2.American Society of Anesthesiologists physical status I to III; 3.Scheduled for 1- to 3-level posterior lumbar or thoracic decompression and fusion surgery due to degenerative spinal disease.
Exclusion criteria
Exclusion criteria: Pain or psychiatric disorders that may interfere with postoperative pain assessment; Allergy to any component of multimodal analgesia or local anesthesia; Acute phase of infection; Spinal metastatic malignancy; Pregnancy or lactation; Patient refusal or any other reason deemed by the investigator to make the patient unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total opioid consumption within 72 hours postoperatively (morphine milligram equivalent, MME); | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS at rest and with movement;use of intravenous PCA , such time to first patient-Initiated PCA dose;Sleep quality;Postoperative recovery: the first time to walk, eat, bowel movement, date of discharge, length of hospital stay.;Patient satisfaction;Opioid use in PACU ; | — |
Countries
China
Contacts
Public ContactLi Min
Peking University Third Hospital
Outcome results
None listed