Knee osteoarthritis
Conditions
Interventions
SVF Group:SVF intra-articular injection
SVF combined PRP group:SVF combined with PRP intra-articular injection.
PRP Group:PRP intra-articular injection
Sponsors
Qianxinan Prefecture People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Those who have been diagnosed with early to mid-stage KOA and undergoing conservative treatment; 2. Age 18-70 years old; 3. Kellgren-Lawrence grade I-III for knee osteoarthritis; 4. the patient is able to understand the instructions given by the doctor; 5. Agree to participate in this trial and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Current oral or topical corticosteroids; 2. Immunosuppression due to HIV, chemotherapy, and radiotherapy; 3. use of anticoagulant drugs; 4. Active inflammation or connective tissue disease lupus erythematosus, rheumatoid arthritis, fibromyalgia.; 5. Severe cardiac disease or active lung disease requiring medication; 6. skeletal defects; 7. secondary OA; 8. Severe local or systemic diseases; 9. Allergy to local anesthetics; 10. Corticosteroid injections within 3 months; 11. Active infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis Index, WOMAC;Lequesne score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Range of motion;Visual analogue scale; | — |
Countries
China
Contacts
Public ContactWu Jun
Qianxinan Prefecture People's Hospital
Outcome results
None listed