Primary osteoarthritis of the knee
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Voluntary participation and written informed consent; 2.undertake to comply with research procedures and cooperate with the implementation of the whole process of research; 3.Age >=45 years old, gender unlimited; 4. According to the classification of osteoarthritis, at least one knee has primary knee osteoarthritis; 5.The patient is generally in good condition, without serious complications such as organ and blood system diseases; 6. During the trial, patients used smart phones and wechat apps and were willing to answer calls in time;
Exclusion criteria
Exclusion criteria: 1. A body mass index of 36kg/m^2 or above; 2. Combined with serious cardiovascular and cerebrovascular, respiratory, digestive, urinary, nervous, hematopoietic, endocrine and other primary diseases (such as unstable angina pectoris, COPD, severe osteoporosis, uncontrolled hypertension, defined as systolic blood pressure >150mmHg or diastolic blood pressure >100mmHg), As well as a history of alcohol or drug abuse, mental illness; 3.Arthritis caused by traumatic arthritis, infectious arthritis, rheumatoid arthritis, neurotrophic arthritis, avascular necrosis of bone, gouty arthritis, dermatomyositis, psoriatic arthritis, ankylosing spondylitis, systemic lupus erythematosus and other causes; 4. There are obvious motor system diseases and affect normal walking. 5.Have a history of surgery affecting daily functional activities such as heart stents and organ operations, or have a surgical plan within the future study period; 6.History of knee drug injection within 3 months; 7. Those who require/take other lower limb physical therapy and rehabilitation treatment; 8.Patients who had participated in other clinical studies within 4 weeks prior to enrollment; 9.Patients who do not accept the randomly assigned treatment plan and do not comply with the doctor's advice; 10. Patients deemed unsuitable for inclusion in this study by the study physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxford knee assessment;At the start of the clinical trial; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxford gait analysis;Plain X-ray of knee joint;30s sitting-erect test;6 minutes walking distance test; | — |
Countries
China
Contacts
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology