Hepatocellular carcinoma (HCC)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged 18-85 years; 2.Patients who strictly met the clinical diagnostic criteria for HCC or were definitively diagnosed with HCC through histopathological or cytological examination; 3.Availability of well-preserved histopathological slides with definitive pathological classification; 4.Histologically confirmed or radiologically diagnosed presence of portal vein tumor thrombus; 5.Has not received systemic treatment or surgical treatment for HCC before. 6.Child-Pugh class A or B liver function classification.
Exclusion criteria
Exclusion criteria: 1. Other primary malignant tumors outside the liver are present or accompanied by the medical history; 2. The tumor involves more than 70% of the liver parenchyma; 3. Prior systemic or local therapy, including surgery, radiotherapy, TACE, HAIC, radiofrequency ablation, percutaneous ethanol injection, and cryoablation; 4. Presence of clinically relevant ascites with a Child-Pugh ascites score of 3; 5. Unable to obtain histological sections; 6. Presence of other organ diseases; 7. Inability to obtain sufficient follow-up data without cooperation during the follow-up period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Conversion rate of the period;Success rate of schedule delay reduction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease control rate, DCR;Objective response rate, ORR; | — |
Countries
China
Contacts
The First Affiliated Hospital of Xi'an Jiaotong University