Obesity
Conditions
Interventions
Lidocaine Group:In the lidocaine group, 2% lidocaine (1.5mg/kg) was intravenously injected before anesthesia induction. Two minutes later, sufentanil (0.2µg/kg) and propofol (2mg/kg) were intravenousl
Saline Group:Patients in the normal saline group received 0.9% normal saline (0.075 ml/kg) before anesthesia induction. Two minutes later, sufentanil (0.2 µg/kg) and propofol (2 mg/kg) were intravenou
Sponsors
The First Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) Body Mass Index (BMI) >= 28 kg/m^2; (2) American Society of Anesthesiologists (ASA) grade I-II; (3) Age 18 - 50 years old; (4) NYHA cardiac function classification I-II; (5) Voluntary signing of informed consent form.
Exclusion criteria
Exclusion criteria: (1) Have chronic lung diseases, such as chronic obstructive pulmonary disease, bronchial asthma, etc.; (2) Have severe arrhythmia; (3) Have severe dysfunction of the heart, lungs, liver or kidneys; (4) Have central nervous system diseases or neurological and mental disorders; (5) Have used sedative-hypnotic drugs or analgesics for more than 3 months; (6) Are allergic to lidocaine, propofol and opioid drugs; (7) Refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time when the end-expiratory carbon dioxide waveform first becomes a straight line;The duration of the straight line in the end-expiratory carbon dioxide waveform;Frequency of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Propofol dosage;Gastroscopy examination time;Recovery time;Target recovery time;Duration of stay in the post-anesthesia recovery room;Vital signs;Score of exposure degree of the cardia;Doctor Satisfaction Score;Patient satisfaction score;Visual Analogue Pain Score;Low blood pressure;Bradycardia;Hiccups;Choking cough;Pain from propofol injection;Nausea and vomiting;Intraoperative Awareness; | — |
Countries
China
Contacts
Public ContactBin Deng
The First Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed