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Long-term Outcomes of Patients with Intermittent Exotropia: A Prospective Cohort Study

Long-term Outcomes of Patients with Intermittent Exotropia: A Prospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105109
Enrollment
Unknown
Registered
2025-06-30
Start date
2025-07-20
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intermittent exotropia

Interventions

Visual training group:

Sponsors

The Zhongshan Ophthalmic Center,Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 17 Years

Inclusion criteria

Inclusion criteria: Observation group 1. Age 8~17 years old, gender is not limited; 2. Best corrected visual acuity of 0.8 or above in both eyes; 3. No anisometropia (the difference in the magnification of the two eyes < 2.50D, and the difference in cylindrical magnification <1.00D); 4. The far-oblique viewing angle and the near-oblique viewing angle are both between 15~35 prism degrees (triangular prism alternate shielding test); 5. The sum of the distance and near intermittent exotropia control scores (Office control scores) is greater than or equal to 2 points and less than or equal to 6 points; 6. Measurable stereoscopic vision at far or near with no evidence of deterioration; 7. Receiving treatment with alternate masking during the follow-up process; 8. Patients sign the informed consent form and voluntarily participate. Visual training group 1. Age 8~17 years old, gender is not limited; 2. Best corrected visual acuity of 0.8 or above in both eyes; 3. No anisometropia (the difference in the magnification of the two eyes < 2.50D, and the difference in cylindrical magnification <1.00D); 4. The far-oblique viewing angle and the near-oblique viewing angle are both between 15~35 prism degrees (triangular prism alternate shielding test); 5. The sum of the distance and near intermittent exotropia control scores (Office control scores) is greater than or equal to 2 points and less than or equal to 6 points; 6. Measurable stereoscopic vision at far or near with no evidence of deterioration; 7. Receiving only visual training therapy during the follow-up process; 8. Patients sign the informed consent form and voluntarily participate. Surgery group 1. Age 8~17 years old, gender is not limited; 2. Best corrected visual acuity of 0.8 or above in both eyes; 3. No anisometropia (the difference in the magnification of the two eyes < 2.50D, and the difference in cylindrical magnification <1.00D); 4. The far-oblique viewing angle and the near-oblique viewing angle are both between 15~35 prism degrees (triangular prism alternate shielding test); 5. The sum of the distance and near intermittent exotropia control scores (Office control scores) is greater than or equal to 2 points and less than or equal to 6 points; 6. Measurable stereoscopic vision at far or near with no evidence of deterioration; 7. Surgical treatment only during the follow-up process; 8. Patients sign the informed consent form and voluntarily participate.

Exclusion criteria

Exclusion criteria: Observation group 1. The vertical oblique angle angle is greater than or equal to 5 prisms; 2. A-V sign; 3. Presence of extraocular muscle paralysis or limitations; 4. History of previous ocular surgery; 5. Presence of amblyopia or ocular organic disease; 6. History of intermittent exotropia treatment; 7. Presence of neurological and other systemic diseases. Visual training group 1. The vertical oblique angle angle is greater than or equal to 5 prisms; 2. A-V sign; 3. Presence of extraocular muscle paralysis or limitations; 4. History of previous ocular surgery; 5. Presence of amblyopia or ocular organic disease; 6. History of intermittent exotropia treatment; 7. Presence of neurological and other systemic diseases. Surgical group 1. The vertical oblique angle angle is greater than or equal to 5 prisms; 2. A-V sign; 3. Presence of extraocular muscle paralysis or limitations; 4. History of previous ocular surgery; 5. Presence of amblyopia or ocular organic disease; 6. History of intermittent exotropia treatment; 7. Presence of neurological and other systemic diseases.

Design outcomes

Primary

MeasureTime frame
Cure rate;

Secondary

MeasureTime frame
Binocular summation function;Fixation stability;Electroencephalogram;Positive fusional convergence;Fusion suppression examination;

Countries

China

Contacts

Public ContactJinrong Li

The Zhongshan Ophthalmic Center,Sun Yat-sen University

lijinrong@gzzoc.com+86 13763312661

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026