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Effects of non-invasive spinal cord electrical stimulation based ontemporally interfering in chronic consciousness disorders

Effects of non-invasive spinal cord electrical stimulation based ontemporally interfering in chronic consciousness disorders

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105103
Enrollment
Unknown
Registered
2025-06-30
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

disturbance of consciousness

Interventions

control group:None
temporal interference group:None

Sponsors

Zhejiang Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Meet the international diagnostic criteria for MCS established by Giacino in 2002 or the UWS diagnostic criteria proposed by Laureys in 2010; 2.Duration of illness >=28 days, with no tendency towards improvement in consciousness within the past month; 3.No sedative or anti-epileptic drugs (sodium or calcium channel blockers) have been used within the past month; 4.Vital signs are stable; 5.No obvious brain edema, hydrocephalus, or severe cerebral atrophy; 6.Age range of 18-75 years; 7.Patient's family member signs informed consent form.

Exclusion criteria

Exclusion criteria: 1. History of previous neurological or psychiatric illness; 2. History of previous head or brain trauma; 3. History of tumor; 4. Taking sedative or anti-epilepsy drugs within the past month; 5. Unstable vital signs; 6. Skull defect; 7. Patient's family members refuse to sign informed consent form.

Design outcomes

Primary

MeasureTime frame
Behavioral improvement;The degree of improvement in cerebral hemodynamics after the end of treatment;

Secondary

MeasureTime frame
The improvement of brain electrical activity after the end of treatment;Behavioral improvement;Behavioral improvement;

Countries

China

Contacts

Public ContactZehao Sheng

Zhejiang Provincial People's Hospital

zryszh@163.com+86 152 6881 1455

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026