Sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Sepsis: Patients were clinically diagnosed with sepsis based on symptoms, signs, and clinical biochemical indicators, with confirmed bacterial infection by microbiological testing and clinical manifestations consistent with sepsis. 2.Non-sepsis: Severe patients without clinical evidence of bacterial infection or microbiologically confirmed absence of bacterial pathogens.
Exclusion criteria
Exclusion criteria: 1.Concurrent primary infections at other sites or confirmed infections with non-bacterial pathogens. 2.Patients with malignancies or other immunocompromising conditions that may confound the study outcomes were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunophenotyping of peripheral blood leukocytes;Single cell transcriptome sequencing of peripheral blood; | — |
Countries
China
Contacts
Children's Hospital,Zhejiang University School of Medicine