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The effect of repetitive transcranial magnetic stimulation synchronized with functional electrical stimulation on upper limb motor function after stroke

The effect of repetitive transcranial magnetic stimulation synchronized with functional electrical stimulation on upper limb motor function after stroke

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105093
Enrollment
Unknown
Registered
2025-06-29
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Simultaneous Treatment Group:Treatment of repetitive transcranial magnetic stimulation synchronized with functional electrical stimulation
Combined Treatment Group:Combined treatment of repetitive transcranial magnetic stimulation and functional electrical stimulation
Conventional Treatment Group:Conventional rehabilitation treatment

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosed by cranial CT or MRI of the brain and meeting the diagnostic criteria for ischemic stroke; 2.Patients who have had their first stroke; 3.Patients with functional impairment of the unilateral upper limb (the dominant hand); 4.The course of the disease is within half a year; 5.The age range is from 30 to 75 years old; 6.Without mental diseases, having stable vital signs, clear consciousness, a Mini-Mental State Examination (MMSE) score of >= 17 points, and being able to cooperate with the evaluation and treatment; 7.The muscle tone of the flexing and extending of the elbow and the flexing and extending of the wrist of the hemiplegic upper limb is <= Grade 1+; 8.Obtaining the consent of the patient and the patient's close relatives and having them sign the informed consent form before enrollment;

Exclusion criteria

Exclusion criteria: 1.There is a history of trauma such as upper limb fractures in the past, and the upper limb function was already impaired before the current onset; 2.Suffering from severe heart and lung diseases or having insufficient liver and kidney functions; 3.The condition is unstable, in the progressive stage of stroke or with recurrence; 4.Personal or family history of epilepsy and mental illness; 5.Implantation of a cardiac pacemaker or intracranial metal implantation; 6.Due to reasons such as the patient's combined severe cognitive impairment or aphasia, the patient is unable to cooperate; 7.Taking medications that can change the excitability of the cerebral cortex (sedatives, antidepressants);

Design outcomes

Primary

MeasureTime frame
The upper limb part of the Fugl-Meyer Assessment Scale (FMA-UE);

Secondary

MeasureTime frame
The Modified Barthel Index;Surface electromyography;National Institute of Health Stroke scale;

Countries

China

Contacts

Public Contactgujianxiong

Affiliated Hospital of Guangdong Medical University

13828260521@163.com+86 138 2826 0521

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026