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The Novel High-Flow Positive Airway Pressure Oxygen Therapy in Correcting Hypoxemia in Patients with Mild to Moderate Acute Respiratory Distress Syndrome

The Novel High-Flow Positive Airway Pressure Oxygen Therapy in Correcting Hypoxemia in Patients with Mild to Moderate Acute Respiratory Distress Syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105079
Enrollment
Unknown
Registered
2025-06-27
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory distress syndrome (ARDS)

Interventions

Control group:Patients received high-flow humidified oxygen therapy(AIRVOTM2) utilizing a respiratory humidification therapeutic device
Experimental group:The novel developed high-flow humidification oxygen therapy device(HVHF) was utilized for both humidification and high-flow oxygen therapy

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. The patient is >= 18 years old and meets the diagnostic criteria for mild to moderate ARDS; 2. The patient has an endotracheal tube (endotracheal intubation or tracheotomy tube); 3. Informed consent of the patient or (and) family members.

Exclusion criteria

Exclusion criteria: 1. Patients with pregnancy and terminal tumor; 2. History of airway injury, pulmonary trauma, lung surgery; 3. Phrenic neuromuscular injury and myasthenia gravis associated with neurological diseases; 4. Various types of shock that are difficult to correct (the mean arterial pressure is still <65mmHg in the case of vasoactive drug use).

Design outcomes

Primary

MeasureTime frame
Oxygenation Index(PaO2/FiO2);

Countries

China

Contacts

Public ContactMei Yang

Shenzhen Second People's Hospital

yangmei3056@163.com+86 135 0968 2339

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026