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Risk Factors for intraoperative Hypothermia and Effect of low dose Norepinephrine infusion on preventing intraoperative Hypothermia

Risk Factors for intraoperative Hypothermia and Effect of low dose Norepinephrine infusion on preventing intraoperative Hypothermia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105071
Enrollment
Unknown
Registered
2025-06-27
Start date
2025-07-14
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative hypothermia

Interventions

Experimental group:During anesthesia induction, norepinephrine was pumped at an initial speed of 0.05 µ g kg-1 min-1, and the pump speed was dynamically adjusted at 0.01-0.10 µ g kg-1 min-1.
Control group:Normal saline with the same pump speed as the intervention drugs in the experimental group.

Sponsors

XuanCheng People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.ASA ?-?; 2.The patient has good compliance and can cooperate with postoperative follow-up; 3. It is planned to undergo non-cardiac elective surgery under general anesthesia, and the estimated operation time is > 30min;; 4.Age > 18 years old;

Exclusion criteria

Exclusion criteria: 1. patients with norepinephrine drug allergy; 2. Hypertensive patients without treatment or poor control; 3. Patients with preoperative hypotension or hemodynamic instability; 4. Patients with heart failure, arrhythmia, myocardial ischemia and sinus bradycardia; 5. Patients complicated with aneurysm who need strict blood pressure control during operation; 6. Patients with severe liver and kidney dysfunction; 7. Pregnant or lactating patients;

Design outcomes

Primary

MeasureTime frame
Intraoperative core temperature;

Secondary

MeasureTime frame
Intraoperative body surface temperature;Postoperative complications;Recovery time;Perioperative temperature;First exhaust defecation time;First time to walk in the fields;Length of Stay;blood gas analysis;liquid intake and output;Rinse solution dosage;Norepinephrine dosage;Perioperative hemodynamics;

Countries

China

Contacts

Public ContactHanyu Wang

XuanCheng People's Hospital

whamyu@163.com+86 177 1829 1880

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026