Acute Gastrointestinal Injury (AGI)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of AGI Western medicine and the syndrome of spleen deficiency and qi stagnation in traditional Chinese medicine. 2. Full informed consent of the research subject himself or his legal guardian. 3. Can tolerate treatment with traditional Chinese medicine decoction.
Exclusion criteria
Exclusion criteria: 1. It does not meet the diagnostic criteria of AGI Western medicine and the spleen deficiency and qi stagnation syndrome of traditional Chinese medicine. 2. At the time of admission to the ICU, the patient had gastrointestinal perforation, massive gastrointestinal bleeding, intestinal ischemia and necrosis, intestinal fistula, intestinal surgery, intestinal obstruction and other intestinal pathologies 3. Those who are unable to take Chinese medicine for various reasons and give up continuing treatment 4. Do not agree with the treatment of Chinese herbal decoction, or are allergic to Chinese medicine 5. Have gastrointestinal malignancy or end-stage malignancy 6. AGI patients who have been treated for less than 7 days or have given up treatment or died during treatment 7. Failure to implement the intervention as prescribed, and the efficacy cannot be determined. 8. Serious adverse reactions, complications, special physiological changes, etc., which are difficult to continue treatment. 9. Use of other drugs that affect the results of this study. 10. Those who do not have enteral nutrition conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastrointestinal motility index;Biological indicators of intestinal barrier function impairment;AGI rating, gastrointestinal dysfunction score;Severity and prognosis: APACHE II score, SOFA score, 28d mortality; | — |
Countries
China
Contacts
Department of Critical Care Medicine, Women and Children's (Sixth People's) Hospital, Fuyang City, Anhui Province