Post-stroke dysphagia
Conditions
Interventions
Gold Standard:(1) Clinical manifestations include symptoms such as dysphagia, coughing or choking, or food residue, and bedside swallowing assessment (e.g., water swallowing test) indicates abnormal s
Index test:Multi-channel Electromyography (EMG):
Surface EMG of the Suprahyoid Muscle Group/Geniohyoid Muscle: Records the onset time point of lingual bolus propulsion during the oral phase of swallow
Sponsors
Shanghai University of Traditional Chinese Medicine, School of Rehabilitation
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for the Case Group: Age between 30 and 80 years old. Meet the diagnostic criteria for stroke and have a first-time onset. Have been assessed as having dysphagia. Be conscious and have stable vital signs, and be able to cooperate in completing the relevant examinations for this study. Willingly sign the informed consent form for this study. Inclusion Criteria for the Healthy Control Group: Age between 30 and 80 years old. Be able to smoothly swallow 30 milliliters of warm water in one go within 5 seconds, without obvious aspiration, and without experiencing choking, suffocation, or other symptoms of swallowing difficulty during the process. Have no history of stroke or other neurological diseases. Willingly sign the informed consent form for this study.
Exclusion criteria
Exclusion criteria: (1) Presence of other neurological diseases (such as Parkinson's disease, Alzheimer's disease, multiple sclerosis, etc.). (2) Abnormal anatomical structures of the pharynx and larynx or postoperative lesions (such as after laryngeal cancer surgery, patients with tracheostomy). (3) Presence of severe cardiopulmonary dysfunction or other terminal illnesses. (4) Presence of psychological or cognitive impairments that prevent cooperation with the examination. (5) Pregnant or breastfeeding women, or those planning to conceive in the near future. (6) Presence of contraindications to cricopharyngeal electromyography, such as patients with a tendency to bleed, those with a pacemaker or cardiac defibrillator, and those prone to recurrent or systemic infections. (7) Presence of contraindications to contrast-enhanced CT, such as patients allergic to iodine-containing contrast agents, those with hyperthyroidism, severe renal insufficiency, or diabetic patients taking biguanide medications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of EMG activity of suprahyoid/submental muscles;Duration of laryngopharyngeal mechanogram;Duration of the inhibition of the CP muscle EMG activity; Interval between onset of EMG activity of suprahyoid/submental muscles and onset of laryngopharyngeal mechanogram;Accuracy;Sensitivity;Specificity;Negative Predictive Value, NPV; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive Predictive Value, PPV; | — |
Countries
China
Contacts
Public ContactWan Ping
School of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed