Pain after fracture surgery
Conditions
Interventions
PO -DEX group:Oral dexamethasone
IV-DEX group:Intravenous dexamethasone
Sponsors
Wenzhou People's Hospita
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Adults who have had unilateral forearm or hand bone surgery; 2. ASA Rating: 1-3; 3. BMI is 18-30kg.m^2 (minimum weight 50kg);
Exclusion criteria
Exclusion criteria: 1. Pregnant women; 2. Patients who are unable to provide informed consent; 3. Patients with contraindications to brachial plexus block (e.g., impaired respiratory function, infection at the puncture site, or a history of brachial plexus injury); 4. Patients with contraindications to dexamethasone use (e.g., poorly controlled hypertension or diabetes, gastric or duodenal ulcers, severe electrolyte imbalance); 5. Patients allergic to the study drug or local anesthetics; 6. Patients taking more than 30 mg of oral morphine equivalents per day; 7. Patients taking more than 5 mg of oral prednisone equivalents per day; 8. Patients with a history of alcohol or drug abuse; 9. Glaucoma; 10. Patients who require other surgical interventions during the study period; 11. Trauma patients who require opioid therapy during the study period;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the time from removal of the block needle until the first sensation of pain in the surgical area (numerical rating scale > 0).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scores;Postoperative nausea and vomiting;Serious adverse events 30 days after surgery;Blood sugar levels;Cumulative oral morphine equivalent;Sleep quality on the first and second night after surgery;Biceps motor recovery time;Adverse events 48 hours postoperatively; | — |
Countries
China
Contacts
Public ContactQian Zhuo
Wenzhou People's Hospita
Outcome results
None listed